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Mesterolon is an oral anabolic steroid, a synthetic product of the male hormone testosteron. The drug has shown value in treating men with mental health issues, such as depression, anxiety and bipolar disorders. The drug also is commonly used to treat sexual dysfunction, including low sperm count. Additionally, mesterolon may enhance the effectiveness of other steroids. Interestingly, unlike other steroids, the drug shows little value for bodybuilding, but has the same health risks involved in steroid use for that purpose.

During the late 1970s, doctors who performed studies on mesterolon concluded that the drug could be used to treat depression in some men. Patients with symptoms of anxiety and low sex drive reported improvement with low doses of the steroid. During the study, higher doses proved helpful to patients with dysthymia and bipolar depression as well. Since this time, newer studies have shown that patients taking a placebo improved at the same rate as patients taking mesterolon, leading medical professionals to believe that better drug options exit.
Mesterolon is often used as an antiestrogenic treatment and may be used by those who have had a poor reaction to testosteron treatments. The drug has shown to be beneficial in treating sexual dysfunction, impotency and low libido. Mesterolon binds to estrogen receptors, reducing their activity, which not only reduces estrogen production, but also encourages natural testosteron production in the body.